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    SPDR® S&P® Biotech ETF XBI

    Important Risk Disclosure

    In general, ETFs can be expected to move up or down in value with the value of the applicable index. Although ETF shares may be bought and sold on the exchange through any brokerage account, ETF shares are not individually redeemable from the Fund. Investors may acquire ETFs and tender them for redemption through the Fund in Creation Unit Aggregations only. Please see the prospectus for more details.

    Equity securities may fluctuate in value in response to the activities of individual companies and general market and economic conditions.

    Funds investing in a single sector may be subject to more volatility than funds investing in a diverse group of sectors.

    Because of their narrow focus, sector funds tend to be more volatile than broadly diversified funds and generally result in greater price fluctuations than the overall market.

    Non-diversified fund may invest in a relatively small number of issuers, a decline in the market value may affect its value more than if it invested in a larger number of issuers. While the Fund is expected to operate as a diversified fund, it may become non-diversified for periods of time solely as a result of changes in the composition of its benchmark index.

    The Fund may not purchase securities of any issuer if, as a result, more than 5% of the Fund’s total assets would be invested in that issuer’s securities; except as may be necessary to approximate the composition of its target index. This limitation does not apply to obligations of the U.S. government or its agencies or instrumentalities.

    Passively managed funds hold a range of securities that, in the aggregate, approximates the full Index in terms of key risk factors and other characteristics. This may cause the fund to experience tracking errors relative to performance of the index.

    While the shares of ETFs are tradable on secondary markets, they may not readily trade in all market conditions and may trade at significant discounts in periods of market stress.

    ETFs trade like stocks, are subject to investment risk, fluctuate in market value and may trade at prices above or below the ETFs net asset value. Brokerage commissions and ETF expenses will reduce returns.

    Before investing, consider the funds' investment objectives, risks, charges and expenses. To obtain a prospectus or summary prospectus which contains this and other information, call 1-866-787-2257 download a prospectus or summary prospectus now, or talk to your financial advisor. Read it carefully before investing.

    NAV

    NAV

    The market value of a mutual fund's or ETFs total assets, minus liabilities, divided by the number of shares outstanding.

    $122.30

    as of May 13 2021

    Base Currency

    USD

    Assets Under Management

    $7,105.64 M

    as of May 13 2021

    Gross Expense Ratio

    Gross Expense Ratio

    The fund's total annual operating expense ratio. It is gross of any fee waivers or expense reimbursements. It can be found in the fund's most recent prospectus.

    0.35%

    Quick Links

    Key Features

    Key Features

    • The SPDR® S&P® Biotech ETF seeks to provide investment results that, before fees and expenses, correspond generally to the total return performance of the S&P® Biotechnology Select IndustryTM Index (the “Index”)
    • Seeks to provide exposure to the Biotechnology segment of the S&P TMI, which comprises the following sub-industries: Biotechnology
    • Seeks to track a modified equal weighted index which provides the potential for unconcentrated industry exposure across large, mid and small cap stocks
    • Allows investors to take strategic or tactical positions at a more targeted level than traditional sector based investing

    About this Benchmark

    About this Benchmark

    The S&P Biotechnology Select IndustryTM represents the biotechnology segment of the S&P Total Market Index (“S&P TMI”). The S&P TMI is designed to track the broad U.S. equity market. The biotechnology segment of the S&P TMI comprises the Biotechnology sub-industry. The Index is modified equal weighted.

    Fund Information as of May 13 2021

    Fund Information as of May 13 2021
    Benchmark Inception Date Options Available Gross Expense Ratio

    Gross Expense Ratio

    The fund's total annual operating expense ratio. It is gross of any fee waivers or expense reimbursements. It can be found in the fund's most recent prospectus.

    		 Base Currency Investment Manager Management Team
    S&P Biotechnology Select Industry Index Jan 31 2006 Yes 0.35% USD SSGA Funds Management, Inc. Global Equity Beta Solutions
    Benchmark S&P Biotechnology Select Industry Index
    Inception Date Jan 31 2006
    Options Available Yes
    Gross Expense Ratio

    Gross Expense Ratio

    The fund's total annual operating expense ratio. It is gross of any fee waivers or expense reimbursements. It can be found in the fund's most recent prospectus.

    		 0.35%
    Base Currency USD
    Investment Manager SSGA Funds Management, Inc.
    Management Team Global Equity Beta Solutions
    Distributor Distribution Frequency
    State Street Global Advisors Funds Distributors, LLC Quarterly
    Distributor State Street Global Advisors Funds Distributors, LLC
    Distribution Frequency Quarterly

    Listing Information as of May 13 2021

    Listing Information as of May 13 2021
    Exchange Listing Date Trading Currency Ticker CUSIP ISIN
    NYSE ARCA EXCHANGE Feb 06 2006 USD XBI 78464A870 US78464A8707
    Exchange NYSE ARCA EXCHANGE
    Listing Date Feb 06 2006
    Trading Currency USD
    Ticker XBI
    CUSIP 78464A870
    ISIN US78464A8707

    Fund Characteristics as of May 13 2021

    Fund Characteristics as of May 13 2021
    Est. 3-5 Year EPS Growth

    Estimated 3-5 Year EPS Growth

    Based on the underlying holdings of the fund. The actual earnings estimates for the underlying holdings are provided by FactSet, First Call, I/B/E/S Consensus, and Reuters and are used to calculate a mean 3-5 year EPS growth rate estimate.

    		 Number of Holdings Price/Book Ratio

    Price/Book Ratio

    The weighted harmonic average of closing market price divided by the most recent reported book value for each security in the fund's portfolio as calculated for the last twelve months.

    		 Price/Earnings Ratio FY1

    Price/Earnings Ratio FY1

    The weighted harmonic average of current share price divided by the forecasted one year earnings per share for each security in the fund. Negative and positive outliers are included in the calculation.

    		 Weighted Average Market Cap
    14.35% 191 4.35 10.75 $8,438.50 M
    Est. 3-5 Year EPS Growth

    Estimated 3-5 Year EPS Growth

    Based on the underlying holdings of the fund. The actual earnings estimates for the underlying holdings are provided by FactSet, First Call, I/B/E/S Consensus, and Reuters and are used to calculate a mean 3-5 year EPS growth rate estimate.

    		 14.35%
    Number of Holdings 191
    Price/Book Ratio

    Price/Book Ratio

    The weighted harmonic average of closing market price divided by the most recent reported book value for each security in the fund's portfolio as calculated for the last twelve months.

    		 4.35
    Price/Earnings Ratio FY1

    Price/Earnings Ratio FY1

    The weighted harmonic average of current share price divided by the forecasted one year earnings per share for each security in the fund. Negative and positive outliers are included in the calculation.

    		 10.75
    Weighted Average Market Cap $8,438.50 M

    Index Characteristics as of May 13 2021

    Index Characteristics as of May 13 2021
    Est. 3-5 Year EPS Growth Number of Holdings Price/Cash Flow Price/Earnings Price/Earnings Ratio FY1
    14.35% 190 17.03 20.96 10.75
    Est. 3-5 Year EPS Growth 14.35%
    Number of Holdings 190
    Price/Cash Flow 17.03
    Price/Earnings 20.96
    Price/Earnings Ratio FY1 10.75

    Index Statistics as of May 13 2021

    Index Statistics as of May 13 2021

    Average Size
    Size Range
    Weighted Average Market Cap Mean Median Largest Smallest
    $8,438.87 M $5,986.68 M $1,418.98 M $205,876.30 M $273.41 M
    Weighted Average Market Cap $8,438.87 M
    Average Size
    Mean $5,986.68 M
    Median $1,418.98 M
    Size Range
    Largest $205,876.30 M
    Smallest $273.41 M

    Yields as of May 13 2021

    Yields as of May 13 2021
    30 Day SEC Yield

    30 Day SEC Yield

    (Also known as Standardized Yield) An annualized yield that is calculated by dividing the net investment income earned by the fund over the most recent 30-day period by the current maximum offering price.

    		 30 Day SEC Yield (Unsubsidized)

    30 Day SEC Yield (Unsubsidized)

    An annualized yield that is calculated by dividing the net investment income earned by the fund over the most recent 30-day period by the current maximum offering price that does not account for expense ratio waivers.

    		 Fund Dividend Yield

    Fund Dividend Yield

    The sum of the most recent 12 dividends within the past 365 days divided by Net Asset Value per share, expressed as a percentage.

    		 Index Dividend Yield

    Index Dividend Yield

    The weighted average of the underlyings' indicated annual dividend divided by price, expressed as a percentage.
    -0.10% - 0.26% 0.10%
    30 Day SEC Yield

    30 Day SEC Yield

    (Also known as Standardized Yield) An annualized yield that is calculated by dividing the net investment income earned by the fund over the most recent 30-day period by the current maximum offering price.

    		 -0.10%
    30 Day SEC Yield (Unsubsidized)

    30 Day SEC Yield (Unsubsidized)

    An annualized yield that is calculated by dividing the net investment income earned by the fund over the most recent 30-day period by the current maximum offering price that does not account for expense ratio waivers.

    		 -
    Fund Dividend Yield

    Fund Dividend Yield

    The sum of the most recent 12 dividends within the past 365 days divided by Net Asset Value per share, expressed as a percentage.

    		 0.26%
    Index Dividend Yield

    Index Dividend Yield

    The weighted average of the underlyings' indicated annual dividend divided by price, expressed as a percentage.

    		 0.10%

    Fund Market Price as of May 13 2021

    Fund Market Price as of May 13 2021
    Bid/Ask

    Bid/Ask Mid Point

    (Also known as Mid Price) The price between the best price of the sellers for a trading unit of a given security and the best price of the buyer of a trading unit of a given security.

    		 Closing Price

    Closing Price

    Market Price of last reported trade on the exchange.

    		 Day High Day Low Exchange Volume (Shares)

    Exchange Volume (shares)

    Represents the volume of shares traded on the ETF's primary exchange throughout the previous business day.

    		 Premium/Discount

    Premium/Discount to NAV

    Shows the comparison of the daily net asset value (NAV) and the Midpoint of the closing bid/ask for each of the funds calculated as ((4PM Bid/Ask - Closing NAV) / Closing NAV * 100)

    		 30-Day Median Bid/Ask Spread

    The median bid-ask spread is calculated by identifying national best bid and national best offer ("NBBO") for each Fund as of the end of each 10 second interval during each trading day of the last 30 calendar days and dividing the difference between each such bid and offer by the midpoint of the NBBO. The median of those values is identified and posted on each business day.
    $122.38 $122.48 $126.10 $119.99 2,458,990 0.07% 0.02%
    Bid/Ask

    Bid/Ask Mid Point

    (Also known as Mid Price) The price between the best price of the sellers for a trading unit of a given security and the best price of the buyer of a trading unit of a given security.

    		 $122.38
    Closing Price

    Closing Price

    Market Price of last reported trade on the exchange.

    		 $122.48
    Day High $126.10
    Day Low $119.99
    Exchange Volume (Shares)

    Exchange Volume (shares)

    Represents the volume of shares traded on the ETF's primary exchange throughout the previous business day.

    		 2,458,990
    Premium/Discount

    Premium/Discount to NAV

    Shows the comparison of the daily net asset value (NAV) and the Midpoint of the closing bid/ask for each of the funds calculated as ((4PM Bid/Ask - Closing NAV) / Closing NAV * 100)

    		 0.07%
    30-Day Median Bid/Ask Spread

    The median bid-ask spread is calculated by identifying national best bid and national best offer ("NBBO") for each Fund as of the end of each 10 second interval during each trading day of the last 30 calendar days and dividing the difference between each such bid and offer by the midpoint of the NBBO. The median of those values is identified and posted on each business day.

    		 0.02%

    Premium Discount to NAV Graph and Summary

    The line graph and table below show historical information about the differences between the daily closing price for shares of the fund (as determined by the fund’s listing exchange) and the fund’s net asset value over certain periods. The vertical axis of the line graph shows the premium/discount expressed as a percentage of NAV. The horizontal axis indicates the date at which the premium/discount occurred. The table shows the number of trading days in which the fund traded at a premium or at a discount to NAV.

    x axis: Dates
    y axis: Premium or Discount (bps)

    Number of Days Summary

    Calendar Year 2020 First Quarter of 2021
    Days Traded at Premium
    Number of days the ETF closing price was above the NAV.
    		 106 29
    Days Traded at Discount
    Number of days the ETF closing price was below the NAV.
    		 147 32
    Days Traded at Premium
    Number of days the ETF closing price was above the NAV.
    Calendar Year 2020 106
    First Quarter of 2021 29
    Days Traded at Discount
    Number of days the ETF closing price was below the NAV.
    Calendar Year 2020 147
    First Quarter of 2021 32
    Fund Data

    Because ETFs trade like stocks at current market prices, shareholders may pay more than a fund’s NAV when purchasing fund shares and may receive less than a fund’s NAV when selling fund shares.

    Before investing, consider the funds' investment objectives, risks, charges and expenses. To obtain a prospectus or summary prospectus which contains this and other information, call 1-866-787-2257 download a prospectus or summary prospectus now, or talk to your financial advisor. Read it carefully before investing.

    Fund Net Cash Amount as of May 13 2021

    Fund Net Cash Amount as of May 13 2021
    Net Cash Amount
    -$1,916,347.23
    Net Cash Amount -$1,916,347.23

    Fund Net Asset Value as of May 13 2021

    Fund Net Asset Value as of May 13 2021
    NAV

    NAV

    The market value of a mutual fund's or ETFs total assets, minus liabilities, divided by the number of shares outstanding.

    		 Shares Outstanding Assets Under Management
    $122.30 58.10 M $7,105.64 M
    NAV

    NAV

    The market value of a mutual fund's or ETFs total assets, minus liabilities, divided by the number of shares outstanding.

    		 $122.30
    Shares Outstanding 58.10 M
    Assets Under Management $7,105.64 M
    Most Recent NAV / NAV History

    Fund Performance

    Fund Performance

    • Fund Inception Date: Jan 31 2006
    Performance
    Month End Quarter End

    as of Apr 30 2021

    as of Mar 31 2021

    As Of 1 Month QTD YTD 1 Year 3 Year 5 Year 10 Year Since Inception
    Jan 31 2006
    Fund Before Tax
    NAV Apr 30 2021 0.76% 0.76% -2.89% 46.65% 16.46% 20.66% 19.09% 15.23%
    Market Value Apr 30 2021 0.69% 0.69% -2.84% 46.64% 16.44% 20.64% 19.09% 15.23%
    S&P Biotechnology Select Industry Index Apr 30 2021 0.77% 0.77% -2.86% 46.57% 16.46% 20.68% 18.90% 15.23%
    Fund After Tax
    Return after Taxes on Distributions Apr 30 2021 0.76% 0.76% -2.91% 46.52% 16.40% 20.59% 18.95% 15.11%
    Return after Taxes on Distributions and Sale of Fund Shares Apr 30 2021 0.45% 0.45% -1.71% 27.63% 12.94% 16.91% 16.42% 13.37%
    S&P Biotechnology Select Industry Index Apr 30 2021 0.77% 0.77% -2.86% 46.57% 16.46% 20.68% 18.90% 15.23%
    As Of 1 Month QTD YTD 1 Year 3 Year 5 Year 10 Year Since Inception
    Jan 31 2006
    Fund Before Tax
    NAV Mar 31 2021 -8.24% -3.62% -3.62% 75.31% 15.77% 21.48% 20.20% 15.26%
    Market Value Mar 31 2021 -8.25% -3.50% -3.50% 75.79% 15.82% 21.51% 20.21% 15.26%
    S&P Biotechnology Select Industry Index Mar 31 2021 -8.21% -3.61% -3.61% 75.20% 15.76% 21.50% 20.01% 15.26%
    Fund After Tax
    Return after Taxes on Distributions Mar 31 2021 -8.25% -3.63% -3.63% 75.15% 15.72% 21.42% 20.06% 15.14%
    Return after Taxes on Distributions and Sale of Fund Shares Mar 31 2021 -4.88% -2.14% -2.14% 44.60% 12.39% 17.62% 17.45% 13.39%
    S&P Biotechnology Select Industry Index Mar 31 2021 -8.21% -3.61% -3.61% 75.20% 15.76% 21.50% 20.01% 15.26%

    Performance quoted represents past performance, which is no guarantee of future results. Investment return and principal value will fluctuate, so you may have a gain or loss when shares are sold. Current performance may be higher or lower than that quoted. Performance of an index is not illustrative of any particular investment.  It is not possible to invest directly in an index.

    Performance returns for periods of less than one year are not annualized.  Performance is shown net of fees.

    The market price used to calculate the Market Value return is the midpoint between the highest bid and the lowest offer on the exchange on which the shares of the Fund are listed for trading, as of the time that the Fund's NAV is calculated. If you trade your shares at another time, your return may differ.

    Gross Expense Ratio: 0.35%

    Top Holdings

    Subject to change.

    Top Holdings

    Subject to change.

    Fund Top Holdingsas of May 13 2021
    Index Top Holdingsas of May 13 2021

    Fund Top Holdings as of May 13 2021

    Name Shares Held Total Mkt Cap M Weight
    United Therapeutics Corporation 339,885 $8,680.06 0.93%
    Curis Inc. 4,964,330 $1,196.15 0.91%
    Alkermes Plc 2,791,410 $3,568.45 0.87%
    Alexion Pharmaceuticals Inc. 357,641 $38,309.27 0.87%
    Zentalis Pharmaceuticals Inc. 1,065,978 $2,379.17 0.86%
    Gilead Sciences Inc. 880,654 $86,425.41 0.85%
    Madrigal Pharmaceuticals Inc. 460,042 $2,182.70 0.85%
    Cytokinetics Incorporated 2,375,454 $1,809.95 0.84%
    Regeneron Pharmaceuticals Inc. 114,925 $54,145.03 0.84%
    Amgen Inc. 235,265 $144,827.83 0.83%
    Download All Holdings: Daily

    Index Top Holdings as of May 13 2021

    Name Total Mkt Cap M Weight
    United Therapeutics Corporation $8,680.06 0.93%
    Curis Inc. $1,196.15 0.91%
    Alkermes Plc $3,568.45 0.87%
    Alexion Pharmaceuticals Inc. $38,309.27 0.87%
    Zentalis Pharmaceuticals Inc. $2,379.17 0.86%
    Gilead Sciences Inc. $86,425.41 0.85%
    Madrigal Pharmaceuticals Inc. $2,182.70 0.85%
    Cytokinetics Incorporated $1,809.95 0.84%
    Regeneron Pharmaceuticals Inc. $54,145.03 0.84%
    Amgen Inc. $144,827.83 0.83%

    Sub-Industry Allocation

    Sub-Industry Allocation

    Fund Sub-Industry Allocation as of May 13 2021

    Sector Weight
    Biotechnology 100.00%

    Index Sub-Industry Allocation as of May 13 2021

    Sector Weight
    Biotechnology 100.00%
    Fund Documents
    Tax Documents
    Insights & Resources

    Purchase Information

    Purchase Information

    Buying and Selling ETFs

    ETFs are flexible and easy to trade. Investors buy and sell them like stocks, typically through a brokerage account. Investors can also employ traditional stock trading techniques; including stop orders, limit orders, margin purchases, and short sales using ETFs. They are listed on major US Stock Exchanges.

    ETFs are subject to risk similar to those of stocks including those regarding short-selling and margin account maintenance.

    Ordinary brokerage commissions apply.

    Fund Footnotes

    In general, ETFs can be expected to move up or down in value with the value of the applicable index. Although ETF shares may be bought and sold on the exchange through any brokerage account, ETF shares are not individually redeemable from the Fund. Investors may acquire ETFs and tender them for redemption through the Fund in Creation Unit Aggregations only. Please see the prospectus for more details.

    After-tax returns are calculated based on NAV using the historical highest individual federal marginal income tax rates and do not reflect the impact of state and local taxes. Actual after-tax returns depend on the investor's tax situation and may differ from those shown. The after-tax returns shown are not relevant to investors who hold their fund shares through tax-deferred arrangements such as 401(k) plans or individual retirement accounts.

    Unless Otherwise noted all information contained herein is that of the SPDR S&P Biotech ETF.

    Performance of an index is not illustrative of any particular investment. It is not possible to invest directly in an index.

    Holdings and sectors shown are as of the date indicated and are subject to change. This information should not be considered a recommendation to invest in a particular sector or to buy or sell any security shown. It is not known whether the sectors or securities shown will be profitable in the future.

    As with all stocks, you may be required to deposit more money or securities into your margin account if the equity, including the amount attributable to your ETF shares, declines.

    The S&P Select Industry series is designed to measure the performance of narrow GICS (Global Industry Classification Standard) sub-industries. The S&P Biotech Select Industry Index is an equal-weighted index that draws constituents from the Biotechnology segment of the S&P TMI. Liquidity and market capitalization screens are applied to the index to ensure investability.

    View More Information About Our Firm: FINRA's BrokerCheck 

    ETFs trade like stocks, are subject to investment risk, fluctuate in market value and may trade at prices above or below the ETFs net asset value. Brokerage commissions and ETF expenses will reduce returns.
     

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    Distributor: State Street Global Advisors Funds Distributors, LLC, member FINRA , SIPC,  an indirect wholly owned subsidiary of State Street Corporation. References to State Street may include State Street Corporation and its affiliates. Certain State Street affiliates provide services and receive fees from the SPDR ETFs. ALPS Distributors, Inc., member FINRA, is the distributor for DIA, MDY and SPY, all unit investment trusts. ALPS Portfolio Solutions Distributor, Inc., member FINRA, is the distributor for Select Sector SPDRs. ALPS Distributors, Inc. and ALPS Portfolio Solutions Distributor, Inc. are not affiliated with State Street Global Advisors Funds Distributors, LLC.
     

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    Before investing, consider the funds' investment objectives, risks, charges and expenses. To obtain a prospectus or summary prospectus which contains this and other information, call 1-866-787-2257, download a prospectus or summary prospectus  now, or talk to your financial advisor. Read it carefully before investing.
      

    Not FDIC Insured * No Bank Guarantee * May Lose Value            

                          

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